Alpha-Ketoglutaric Acid is an important biomolecule, one of the important intermediate products in the tricarboxylic acid cycle, a transporter of nitrogen and a symbiotic substance in molecular oxidation.  α‑ Ketoglutaric acid is an important biological molecule, one of the important intermediate products in the tricarboxylic acid cycle, and is a nitrogen transporter and a symbiotic substance in molecular oxidation. It plays an important role in the metabolism of microbial cells and is also an important precursor for the synthesis of multiple chemical book amino acids and proteins. 2-Ketoglutaric acid participates in the tricarboxylic acid cycle in vivo to generate amino acids, and can be used as a dietary supplement.   Our Manufacturer TGYBIO was specialized Supplements. we supply a-Ketoglutaric Acid / 2-Ketoglutaric Acid and BCAA 2:1:1 with high purity 99% for sale, it's very hot selling now, we supply with lowest price and high quality,  you can contact us for free samples and more product details. Product name Alpha-Ketoglutaric Acid CAS 328-50-7 Appearance White powder Molecular Formula                 C5H6O5 Melting Point 113-115 °C Application Nutrition supplement                   α- Ketoglutaric acid can be used as a nutritional enhancer as a component of sports nutritional beverages; It can also be used as organic intermediates, biochemical reagents, matching reagents for liver function testing, and physical enhancement supplements.   1.alpha ketoglutaric acid  used as tricarboxylic acid cycle α- Ketoglutarate is an important metabolic intermediate in the microbial tricarboxylic acid cycle, which is a key node connecting the carbon nitrogen metabolism in cells. It is located after isocitric acid and before succinyl coenzyme A in the cycle. In this part, anaplerotic reaction can be generated through Transamination of glutamic acid α- The purpose of supplementing this intermediate metabolite with ketoglutaric acid can also be achieved through the action of glutamate dehydrogenase on glutamate. 2. alpha-ketoglutaric acid used for Generate amino acids Glutamic acid can generate glutamine under the action of glutamine synthase, which uses a molecule of ATP to produce glutamine phosphate; This intermediate product is attacked by ammonia as a nucleophilic reagent, resulting in the formation of glutamine and inorganic phosphate. 3. alpha ketoglutaric acid used for dietary supplements α- Ketoglutaric acid is sold as a dietary supplement under the trade name AKG or a-KG and is sold to fitness enthusiasts or bodybuilders. The seller claims that this substance can improve performance at the peak of training. The seller claims that this is based on "research indicating that excessive ammonia can bind to α- Ketoglutaric acid is taken away to reduce the numerous problems caused by ammonia poisoning. However, it showed that α- The only effective study on ketoglutarate in reducing ammonia poisoning is only for patients who have undergone hemodialysis.