S-Adenosyl-L-methionine (also called S-adenosyl methionine, S-adenosylmethionine, SAMe, or SAM-e in the United States or ademetionine in Europe, and also often abbreviated as SAM and AdoMet) S-Adenosyl-L-methionine Disulfate Tosylate(SAMe) is synthesized catalyzed by adenosine triphosphate and methionine. Due to its methyl transfer, sulfhydryl transfer and aminopropylation, it participates in a variety of metabolic reactions in the organism, such as the synthesis of nucleic acids, proteins, lipids and secondary metabolites. In addition, it is also a biologically active precursor of coenzyme A and glutathione. S-Adenosyl-L-methionine (SAMe) is a naturally occurring compound found in every living organism. It plays many important roles in the body, including acting as a methyl donor in a wide range of biochemical reactions. SAMe has been studied for its potential therapeutic use in treating depression, osteoarthritis, and liver disease, among other conditions. It is available as a dietary supplement in some countries. S-Adenosyl-L-methionine (SAMe) is a coenzyme involved in methyl group transfers. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase (EC 2.5.1.6). Transmethylation, transsulfuration, and aminopropylation are the metabolic pathways that use SAMe. Although these anabolic reactions occur throughout the body, most SAMe is produced and consumed in the liver. Our Manufacturer TGYBIO was specialized Supplements. we supply S-Adenosyl-L-methionine/S-adenosylmethionine(SAM) SAMe, a-Ketoglutaric Acid / 2-Ketoglutaric Acid and BCAA 2:1:1 with high purity 99% for sale, it's very hot selling now, we supply with lowest price and high quality,  you can contact us for free samples and more product details.   Product name                  S-Adenosyl-L-methionine Disulfate Tosylate CAS No. 97540-22-2/29908-03-0 Appearance White or almost white powder Purity ( HPLC ) 98.0% to105.0% Heavy metals Not more than 10 ppm Loss on drying Not more than 1% Shelf life 24 months Packing 25kg/drum or customized Storage condition Store in cool place and keep container away from sunlight 1> S-Adenosyl-L-Methionine can be added in health care supplements. 2> S-Adenosyl-L-Methionine as a dietary supplement. S-Adenosyl-L-Methionine (SAMe) has been used for a variety of health purposes, including: Depression: SAMe may be effective in treating mild-to-moderate depression. Some studies have shown that it may work as well as prescription antidepressants, with fewer side effects. Osteoarthritis: Taking SAMe may help reduce joint pain and stiffness, as well as improve overall joint function, in people with osteoarthritis. Liver disease: SAMe may help protect liver cells and improve liver function in people with liver disease, including hepatitis and cirrhosis. Fibromyalgia: SAMe may help reduce pain and improve quality of life in people with fibromyalgia. Brain function: Some studies have suggested that SAMe may help improve cognitive function and memory in older adults. It's important to note, however, that more research is needed to fully understand the potential benefits and risks of SAMe supplementation. It's also important to talk to your healthcare provider before starting any new supplement or medication. 1.S-Adenosyl-L-Methionine SAMe is a good nutrition for the liver,can prevent alcohol, drugs and the liver-cell injury; 2.S-Adenosyl-L-Methionine SAMe has remarkable preventive effects on chronic active hepatitis, and other factors caused liver injury,heart disease, cancer and so on. 3.S-Adenosyl-L-Methionine SAMe has been found to be as effective as pharmaceutical treatments for arthritis and major depression as well.