What is Esculin ? Esculin is a saponin extracted from the dried seeds of Horse Chestnut Tree. It is also known as Esculin, Aescin, and Rosskastanie. Escin acts as an astringent, vasoconstrictor, and anti-inflammatory activities. It is commonly used in skin treatments, especially those targeted towards spider veins and varicose veins.Esculin helps to boost circulation and improve vein health. Horse chestnut seed extract is widely used in Europe for chronic venous insufficiency (CVI), a syndrome that may include leg swelling, varicose veins, leg pain, itching, and skin ulcers. Although traditionally recommended for a variety of medical conditions, CVI is the only condition for which there is strong supportive scientific evidence.   Every autumn, the shady horse chestnut tree (Aesculus hippocastanum) produces prickly fruits containing one to three large seeds, or "nuts." In the 1800s, European doctors figured out that an extract made from these seeds could help treat varicose veins, hemorrhoids, and other disorders caused by fragile veins and sluggish circulation. Today, horse chestnut seed extract is still used for these conditions and is particularly popular in Germany, where it ranks among the most common prescription herbal remedies (after ginkgo biloba and St. John's wort). The horse chestnut is also known as the Spanish chestnut. Never take the seeds right off the tree to make a home remedy; the seeds (and other parts of the tree) are poisonous. To be safe, they must be carefully treated to extract the active ingredient. Also, don't confuse seeds from the horse chestnut with seeds ("nuts") of the sweet chestnut (Castanea vesca), a tree that bears delicious chestnuts, ideal for roasting and stuffing into holiday turkeys. Scientists examining the seeds of the horse chestnut identified the main therapeutic ingredient, aescin, which is sometimes described as a group of chemically related substances called "escin." Aescin reduces inflammation and tones up vein walls, allowing blood to flow back to the heart more easily. It appears to accomplish this by plugging up minute holes and microscopic leaks in the tiniest blood vessels, the venules, and in the capillaries. In reinforcing the strength of veins, horse chestnut is believed to also promote their elasticity and prevent swelling and long-term damage to them. Product Name Aescin Latin Name Aesculus chinesis Bge Odor Characteristic Specification 20% 30% 40% 98% Appearance White Powder MOQ 1kg Grade Food Grade Test methold HPLC Storage conditions Store in cool & dry place, Keep away from strong light and heat. Sample Available 1.As raw material of antiedema, relieving pain, easing the pressure, it is widely used in pharmaceutical field; 2.As the product of removing edema, antifatigue and easing the pressure, it is widely used in health industry 3.It used to cure blood circulation disorder and rheumatism; 4.Aesculus chinensis extract can be used in cosmetic products, because it has efficacy of Inflammatory skin resistance. 1. Anti-inflammation, Anti-bacteria, Anti-cancer, Ease pain, Anti-arrhythmic, Anti-histaminic, Anti- cruor . Esculin is a glycoside composed of glucose and a dihydroxycoumarin compound ; 2. Esculin is a product of a coumarin derivative extracted from the bark of flowering ash (Fraxinus ornus; 3. Esculin is used in the manufacturing of pharmaceuticals with venotonic, capillary- strengthening and antiphlogistic action similar to that of Vitamin P; 4.Esculin is a fluorescent dye that can be extracted from the leaves and bark of the horse chestnut tree. You'll need to shine a black (ultraviolet) light on the indicator to get the full effect; 5. Esculin changes from colorless at pH 1.5 to fluorescent blue at pH 2. The main pharmacological actions of esculin include capillary protection and the inhibition of enzymes such as hyaluronidase and collagenase; 6.Esculin improved skin vasculature and is effective in the management of cellulitis Pharmacological effects.